Differences between Tirzepatide & Semaglutide

​

What is Tirzepatide?
Tirzepatide is a natural compound found in the body. It helps perform several important bodily
functions. It is a compound that mimics a class of hormones called ‘glucagon-like peptide-1’ or ‘GLP-1’.
However, it also mimics the effect of another class of hormones called ‘glucose-dependent
insulinotropic polypeptide’ or ‘GIP’. Thus, its ability to mimic two different types of hormones is unique.

 

What is Semaglutide?
Semaglutide is a natural compound that can perform several important bodily functions. Like
tirzepatide, semaglutide mimics the action of the GLP-1 class of hormones. However, it cannot mimic
the effects of GIP hormones in the body. However, this inability to mimic GIP hormones does not make
it less effective than tirzepatide.

How Effective Are These Two Medicines At Managing Weight?
Tirzepatide and semaglutide have different effects on the body. Tirzepatide, the active ingredient in
Mounjaro, mimics the effect of GLP-1 and GIP hormones. Semaglutide, the active ingredient in Wegovy,
only mimics the effect of GLP-1 hormones. Thus, tirzepatide is also called a ‘twincreatin’ medicine as it
mimics two hormone groups.
Scientific trials involving placebos and controls show promising results for tirzepatide. People taking
tirzepatide lost, on average, 22% of their starting weight. People participating in these trails also
undertook important lifestyle changes. They ate a healthier diet and improved their exercise routine.